Drug Delivery: Silica Nanopills for Targeted Anticancer Drug Delivery (Small 36/2015)

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Thiol-functionalized mesoporous silica as nanocarriers for anticancer drug delivery

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Thiol-functionalized mesoporous silica as nanocarriers for anticancer drug delivery

The present study deals with the synthesis andfunctionalization of mesoporous silica nanoparticles as drug delivery platforms. SBA-15 nanorods with high surface area (1010 m2g-1) were functionalized by post grafting method using 3-mercaptopropyl trimethoxysilane (MPTS). The parent and thiol-functionalized SBA-15 nanorods were used as nanocarriers for an anticancer drug (gemcitabine). The charac...

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thiol-functionalized mesoporous silica as nanocarriers for anticancer drug delivery

the present study deals with the synthesis andfunctionalization of mesoporous silica nanoparticles as drug delivery platforms. sba-15 nanorods with high surface area (1010 m2g-1) were functionalized by post grafting method using 3-mercaptopropyl trimethoxysilane (mpts). the parent and thiol-functionalized sba-15 nanorods were used as nanocarriers for an anticancer drug (gemcitabine). the charac...

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ژورنال

عنوان ژورنال: Small

سال: 2015

ISSN: 1613-6810

DOI: 10.1002/smll.201570221